Our paper entitled “A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters” is now published in Nature Chemical Biology. Congrats to Drs. Piatkevich and Jung – the first co-authors of this paper!
It is also on MIT news.
This paper reports a novel genetically encoded molecule named Archon that changes its fluorescent light intensity as a function of the voltage across the cell membrane allowing to directly “image” neuronal voltage activity. This work was led by Prof. Ed Boyden (MIT).